Objective:  To determine frequency of various complications of low birth weight babies during 1st three days of admissions. Patients and Methods: This De- scriptive study (case series) was conducted at Department of Gynecology & Obstetrics and neonatal nursery of pediatric department LUH Hyderabad. All the low birth babies were evaluated for various complications while the data was collected on pre-designed proforma and analyzed in SPSS version 10.00. Results: Out of total 1511 deliveries at LUH Hyderabad, 565 newborn were LBW giving prevalence of 37.4%. Out of these 565 LBW, male newborn were 55.8% and females were 44.2%. Immediate problems with decreasing frequency either alone or in combination in 237 (41.9%) admitted newborn babies out of these 565 LBW babies included jaundice in 40.1%, birth asphyxia in 25.7%, RDS in 21.1%, hypothermia in 19.8%, hypoglycemia in 19.0%, congenital malformations in 6.3%, NEC in 5.1% and IVH in 4.2% babies. Conclusion: Major problems of these children found, included jaundice, birth asphyxia, hypothermia, hypoglycemia, RDS and sepsis.