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Medical Channel Journal
2009, Volume 15, Issue 2 : 72-77
Research Article
Serodiagnosis Of Amoebic Liver Abscess By Indirect Haemagglutination Test
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1
Assistant Professor Department of Pathalogy DOW MEDICAL COLLEGE, KARACHI. Lecturer
2
Dept. of Pathalogy DOW MEDICAL COLLEGE, KARACHI.
3
Professor LIAQUAT MEDICAL COLLEGE & DARUL SIHAT HOSPITAL, KARACHI.
4
Assistant Professor Department of Pathalogy BMSI, JPMC, KARACHI
Received
Aug. 8, 2009
Revised
July 7, 2009
Accepted
June 5, 2009
Published
April 5, 2009
Abstract

OBJECTIVE :  To assess the role of Indirect Haemagglutination Test for the diagnosis of amoebic liver abscess.STUDY  DESIGN :  Comparative StudyPLACE  AND  DURATION : This  study  was  carried  out  at  Basic  medical  Sciences Institute,  JPMC,  Karachi  from  February  2000  to  January  2001.SUBJECTS  AND  METHODS : Blood samples were obtained from 100 cases of amoebic liver abscess  and 100 age matched healthy individuals.  Indirect  haemagglutination test was performed on the serum to see the titres of antibodies to Entamoeba  histolytica. RESULT :  Significant  antibody  titres  ranging  from  1 : 256 - 1 : 4096  were  observed in confirmed cases of amoebic  liver  abscess. While titres were non-significant  in normal subjects. IHA was  found to be 96%  sensitive and 100% specific for the serodiagnosis of amoebic liver abscess

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